This is the first in a series of three proceedings of the 20th Pacific Basin Nuclear Conference (PBNC). This volume covers the topics of Safety and Security, Public Acceptance and Nuclear Education, as well as Economics and Reducing Cost. As one in the most important and influential conference series of nuclear science and technology, the 20th PBNC was held in Beijing and the theme of this meeting was “Nuclear: Powering the Development of the Pacific Basin and the World”. It brought together outstanding nuclear scientist and technical experts, senior industry executives, senior government officials and international energy organization leaders from all across the world. The book is not only a good summary of the new developments in the field, but also a useful guideline for the researchers, engineers and graduate students.